The octet htx instrument monitors up to 96 biosensors simultaneously, enabling labelfree detection for protein quantitation and kinetic characterization at unmatched speed. Fremont, ca prweb april 05, 2017 pall fortebio, the market leader in labelfree biomolecular interaction analysis across academic research, drug discovery and development, process analytics, and manufacturing quality control today announced the launch of the new octet red96e instrument. Mar 03, 2017 the octet platform includes instruments, biosensors, reagents and assay kits for biomolecular interactions analysis in microplates. We offer products that span multiple technology vectors. Octet software is the analytical software suite that has intuitive user interface and powerful data analysis features. The octet software kinetics analysis and reporting user software enabling graph exporting in a number of different formats streamlined data analysis and model fitting within origin 7. Sep 14, 2018 about pall fortebio pall fortebio is a division of pall life sciences that provides analytical systems to accelerate biotherapeutic drug discovery and development. Molecular devices pall fortebio octet red96e labelfree. Octet software provides an intuitive and easy to use inter face for data acquisition and analysis on all octet instruments, enabling labelfree kinetic, affinity. The system has been developed to operate reliably in a regulated environment. Fortebio introduces the octet system technology networks.
Aug 12, 2019 fortebio introduces high precision octet system biosensor for process development rigor published. Octet data analysis ht software enables making customized. Your local fortebio representative can provide detailed information on system capabilities and our extensive library of octet application solutions to help you choose the system thats right for your lab. The systems ability to read 8, 16, 32, 48 or 96 wells in parallel lets you tailor your assay design to maximize analytical throughput or sensitivity. Fortebios octet red96es complete qualification, validation, and support solution ensures compliance in the regulatory space, while allowing for rapid development, optimization, and validation of assay methods. These systems facilitate realtime, labelfree analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. Mar, 2019 relative sialylation results can then be combined in the software with titer data obtained on the octet system to select clones that have high protein expression as well as optimal sialic acid content during early screening in cell line development. Epitope binning by fortebio octet platform creative biolabs. Focused on meeting customers needs to minimize variability from consumables, the. These systems facilitate realtime, labelfree analysis of biomolecular interactions, providing information on. Fortebio is a business unit of molecular devices llc, offering products that span multiple technology vectors including analytical instrumentation and software, clone picking and imaging, and customized engineering solutions.
Summar y octet systems provide an automated solution for maximizing the efficiency of antibody detection and quantitation in biopharmaceutical development and manufacturing processes. Fremont, ca prweb april 05, 2017 pall fortebio, the market leader in labelfree biomolecular interaction analysis across academic research, drug discovery and development, process analytics, and manufacturing quality control today announced the. For more information about pall fortebios octet platform for labelfree, realtime detection of biomolecular interactions, applications. At molecular devices, were committed to ensuring a smooth transition. Fortebio introduces new product for highthroughput glycan screening. Labelfree analytical technologies such as the octet platform from pall fortebio provide a powerful means to obtain accurate information. See the software available in the mac labs and windows labs around campus, lists maintained by cit. Our technology platforms encompass workflows from antibody discovery and cell line development through to biomolecular analysis of the biologic product.
Your local pall fortebio representative can provide detailed information on system capabilities and our extensive library of octet application solutions to help you choose the system thats right for your lab. Fortebio introduces high precision octet system biosensor. The octet red96e system is widely used in analytical core labs for protein structurefunction studies and small molecule screening campaigns. About pall fortebio pall fortebio is a division of pall life sciences that provides analytical systems to accelerate biotherapeutic drug discovery and development. Dec 01, 2012 fortebios octet platform figure 1 provides comprehensive characterization across a range of applications in various stages of drug development, including antibody and protein quantitation.
Aug 11, 2011 octet software continues to rapidly evolve to address the needs of fortebio customers. High throughput octet htx and octet red384 systems fortebio. Developer of analytical systems for protein quantification or characterization of proteinprotein interaction. Octet red384 16channel system offers exceptional speed antibody quantitation, kinetics, epitope binning, and much more.
Focused on meeting customers needs to minimize variability from consumables, the sax2 biosensors are controlled to meet the most. Biomolecular binding kinetics assays on the octet platform 14 introduction direct measurement of biomolecular interactions plays an important role in biotherapeutic drug discovery and development. Measure binding affinities over a range of biomolecular interactions, determine concentrations of engineered proteins or contaminating impurities the octet provides a wealth of information to enable more informed decision making. Octet binding curve rate of increase in optical thickness as the. Displays software, user, and instrument information. Providing technologies to accelerate therapeutics development.
An optional microplate evaporation cover minimises sample loss, enabling up to 12 hours of unattended run time. Tecan offers a variety of sophisticated solutions for protein analysis. Vanderbilt vaccine center acquires octet htx system to. Perfectly suited to operate in gxpregulated environments. Octet systems for biologics characterization youtube. Assays are performed using biosensors, reagent and assay kits in 96 and 384well microplates making it a significantly easier and faster technique than other comparative labelfree technologies.
A design for development approach was incorporated to ensure hasslefree transition and future development needs. Vanderbilt vaccine center acquires octet htx system to speed. The purpose of this document is to describe the procedure for developing a ligand binding kinetics assay on octet qke, red96, red96e. Fortebio introduces high precision octet system biosensor for. Fortebio s octet red96es complete qualification, validation, and support solution ensures compliance in the regulatory space, while allowing for rapid development, optimization, and validation of assay methods. Acornelemental8s design team is proud to have worked with fortebio to deliver the iconic look and feel with operational ease. These comparison tables provide a general guide to the features included in various versions of the software. Octet cfr software octet software comparison user friendly software for data acquisition and analysis. Octet system uses dipandread assay mode avoiding the need of microfluidics, and enables the realtime, labelfree analysis of affinity as well as kinetics. The data analysis ht software is the recommended choice for all new users.
Fortebio is a business unit of molecular devices, offering products that span multiple technology vectors including analytical instrumentation and software, clone picking and imaging, and. Fortebio octet systems enable realtime, labelfree analysis for determination of affinity, kinetics, and antibodyprotein concentration. From robust multimode readers to the integrated labelfree analysis using the fortebio octet platform to protein digestion and maldi spotting, we can streamline your assay development process. Strengthens portfolio with new biosensors for research and development published.
The latest release, version 11, is available for use on all octet systems. Offering both high quality data and high throughput analysis, the octet platform allows you to more thoroughly characterize candidate molecules without extending timelines. Pall fortebios octet data acquisition and data analysis software is rapidly evolving to better address the growing applications and needs of. The instrument is very robust, easy to use and is well supported by an experienced support staff of application scientists, software engineers, service engineers and sales. Robust, labelfree interaction analysis across academic research, drug discovery and development, process analytics, and manufacturing. A customer presentation and exhibit of fortebio s octet system will be at the ibc antibody engineering conference in san diego, december 10 through 14, booth 301. The htx read head provides design flexibility that allows users to analyze, 8, 16, 32, 48, or 96.
The systems ability to read 8, 16, 32, 48 or 96 wells in parallel lets you tailor your assay design to. The localhost option can be useful in developing the automation cli. Developing a robust quantitation assay for monoclonal. On april 30, 2020, sartorius ag acquired life science company fortebio, the former biologics business unit of. Epitope binning by fortebio octet platform when multiple antibodies have similar affinities for a target, determining whether they bind to the same or different epitopes on the target molecule becomes an inevitable step towards evaluating their individual functional potential. Whats new in the octet system data acquisition software, release 7. The octet platform is helping researchers characterize the binding interactions of biomolecules to better understand their safety and efficacy. Data analysis ht has several new features that improve on the capabilities of original data analysis software. The octet platform is highly suited for a fast evaluation of the interactions between these potential key assay inputs and allows for relatively highthroughput method development. Fortebio introduces high precision octet system biosensor for process development rigor published.
The octet data analysis ht software is designed for fast analysis of large datasets from quantitation, kinetic and epitope binning assays. Apr 05, 2017 fremont, ca prweb april 05, 2017 pall fortebio, the market leader in labelfree biomolecular interaction analysis across academic research, drug discovery and development, process analytics, and manufacturing quality control today announced the launch of the new octet red96e instrument. Biolayer interferometry, and discuss options, techniques and considerations for developing. The octet platform includes instruments, biosensors, reagents and assay kits for biomolecular interactions analysis in microplates. Fortebios octet platform figure 1 provides comprehensive characterization across a range of applications in various stages of drug development, including antibody and protein quantitation. Fortebio, a leading supplier of instrumentation for accelerated drug discovery and development, launched the octet htx system, the new flagship member of the octet line. Fortebio s octet red384 system is designed for increased throughput for labelfree protein quantitation and kinetic characterization. Integration of the instrument into an automation system was completely supported by fortebio. Fortebio offers an optional 21 cfr part 11 software for the octet red96e system. The company offers octet family of instruments and related consumables that provide scientists with information about biomolecular interactions in micrplate format for proteins, peptides, dna, rna, and small molecules. Fortebio provides integrated solutions for early stage biologics development. Fortebio offers 21 cfr part 11 software and a full line of gxp products and services as part of the octet red96e gxp package. Molecular devices pall fortebio octet red96e labelfree real.
Compared to the standard biacore system, octet has a higher throughput that provides greater potential in drug development applications. Fortebio acquired by sartorius ag apr 30, 2020 on april 30, 2020, sartorius ag acquired life science company fortebio, the former biologics business unit of molecular devices. Fortebio launches octet htx system for accelerated drug. Pall fortebio launches the octet red96e system for more. Octet software provides an intuitive and easy to use interface for data acquisition and analysis on all octet instruments, enabling labelfree kinetic, affinity, epitope binning, activity, concentration and screening applications. Fortebio pq kits provide rapid and convenient methods to verify. Realtime, labelfree bio analytics for determination of. The octet family of instruments is designed to meet a broad range of application and workflow requirements. Aug 04, 2016 the octet platform is helping researchers characterize the binding interactions of biomolecules to better understand their safety and efficacy. From igg titre to epitope binning, the octet red384 system offers labelfree molecular interaction analysis with stateoftheart high throughput platforms that facilitate the rapid characterisation and development of biologics drug molecules. The octet htx and octet red384 utilize fortebios dip and read technology with the read head dipping into samples in a plate format. Octet systems enable realtime, labelfree analysis for determination of affinity, kinetics, and antibodyprotein concentration. Unmatched versatility for discovery and development.
Fortebio is a venturecapital funded life science company providing analytical systems to accelerate the development. Streamlined, intuitive workflow and friendly software interface for faster assay setup and analysis pall fortebio develops and markets analytical systems that enable realtime analysis of biomolecular interactions. With no fluidics involved, octet systems are highly robust. In most cases, octet will be able to help you or to direct you to where you can find some help. On april 30, 2020, sartorius ag acquired life science company fortebio, the former biologics business unit of molecular devices. User friendly software for data acquisition and analysis. The octet red96e operates with a wide range in temperature 15 40 c. Octet is designed to accelerate antibody development by generating realtime quantitative and kinetics results quickly and easily. Pall fortebio launches the octet red96e system for. Fortebio octet data acquisition and data analysis software is rapidly evolving to better address the growing applications and needs of our customers.
Fortebio acquisition by sartorius molecular devices. Octet platform there the biosensor comes to the sample. Fortebio is a business unit of molecular devices llc based in fremont, ca. Fortebio offers sialic acid kit for glycan screening application. Fortebio offers sialic acid kit for glycan screening. It analyzes multiple plates and experiments together for all types of analyses, reducing analysis time from hours to minute. Get accurate concentration, kinetic constants, and affinity data for proteinprotein, small moleculeprotein and other fastbinding interactions all with dip and read simplicity.
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